This page covers Resveratrol IV Therapy including its benefits. IV League provides mobile Resveratrol IV Therapy.
Many plants produce resveratrol when they are harmed or under stress. It is a component of red wine and offers antioxidants that work in concert to fight cancer. As oral absorption with supplementation is poor, it is intravenously recommended for cancer patients.
It also guards against DNA deterioration, which can result in tumor growth. Additionally, cyclooxygenase, which is known to contribute to tumor formation by encouraging inflammation and cancer cell proliferation, is inhibited by resveratrol.
Additionally, it has been demonstrated that resveratrol increases the activity of several carcinogen-detoxifying enzymes, which is crucial for both the prevention and treatment of cancer. It has been demonstrated to reduce the prevalence of various cancers, including liver cancer, colorectal cancer, and breast cancer.
A class of substances known as polyphenols, which are produced by many plants to combat germs, includes resveratrol. Polyphenols are thought to function as antioxidants. Protect your body from damage that can put us at high risk of illnesses such as cancer and heart disease.
Resveratrol may provide several health advantages, including serving as an antioxidant, according to research.
Resveratrol can lessen allergies and has been shown to have anti-tumor effects, anti-neurological activity, and to operate as an anti-inflammatory drug that may reduce inflammation of the nervous system. improves memory loss and speeds up weight loss.
Benefits of Resveratrol IV Therapy
- Resveratrol stimulates the body’s enzyme Sirtuin, which is crucial for the process of slowing down age and longevity. This serves to slow down ageing, slow down cell degeneration, and help people live longer.
- Aids in DNA repair and shields it from free radical damage. The body’s cells and organs slow down as a result of chemicals and UV rays.
- Resveratrol, a polyphenol found in grape peel extract, is a potent antioxidant that improves skin health and minimizes wrinkles. It has anthocyanin, a pigment or natural coloring agent that gives grape peels their purple hue, which shields it from the sun’s rays and makes it look younger. In addition to having antioxidant characteristics that slow down cell ageing, it also binds free radicals effectively. Antioxidants come in a variety of shapes and sizes, and they work 20 times better than vitamin C and 50 times better than vitamin E. Cellular ageing may be slowed down as a result. Consequently, the cells are in good shape. better skin tone Additionally, collagen breakdown is slowed.
- Helps to make the immune system stronger. Because it has the potential to protect cells and disrupt disorders like amnesia and Parkinson’s disease, which are frequently accompanied by the degradation of the body, sirtuin proteins made from the SIRT-1 gene have the capacity to strengthen the body. heart disease and type 2 diabetes liver illness cancer, lung conditions, etc.
- Helps inhibit Escherichia coli, a pathogenic microorganism in the gastrointestinal tract and causes diarrhea.
- Anti-inflammation reduces inflammation in the body.
- As reducing cholesterol can alter blood lipid levels, it lowers the risk of cardiovascular disease. inhibits blood from clumping and raises HDL (high-density lipoprotein, a good fat) while decreasing LDL (low-density lipoprotein, a harmful fat). lowers the chance of blood vessel blockages. increases circulatory system strength, thereby defending against and lowering the risk of cardiovascular disease.
- It improves insulin function, lowers blood glucose levels, and keeps blood glucose levels in balance, all of which lower the risk of developing diabetes, particularly type 2 diabetes.
- Helps to balance the body to improve metabolic function, as resveratrol stimulates sirt-1 enzymes.
- It helps cells burn more energy, thereby preventing the accumulation of fat. Reduces the risk of metabolic disease and type 2 diabetes.
- Reduces the risk of cancer and cell formation Helps inhibit the distribution of cancer cells and tumor growth.
Parkinson’s disease and Alzheimer’s disease
- Reduces blockage creation, which lowers the likelihood of Parkinson’s illness and Alzheimer’s forgetting. Plaque in the brain slows down the loss of brain neurons.
History of Resveratrol IV
Renaud and De Lorgeril were the first to relate wine polyphenols such as resveratrol, to the potential health benefits attributed to regular and moderate wine consumption (the so called “French Paradox”). Since then, resveratrol has drawn more and more scientific attention, sparking research into its biological effects and countless publications.
First discovered in the roots of the white hellebore (Veratrum grandiflorum O. Loes) in 1940, resveratrol was later discovered in the roots of Polygonum cuspidatum in 1963. Both of these plants are utilised in traditional Chinese and Japanese medicine as anti-inflammatory and anti-platelet agents.
More than 70 plant species have been identified to contain this natural polyphenol, which is also present in trace amounts in some red wines and other foods consumed by humans. Grapes have high amounts, probably as a result of Vitis vinifera’s reaction to a fungus infection.
Resveratrol is a phytoalexin that is produced in plants in reaction to physical harm, UV radiation, and microbial infections. For commercial use, resveratrol is often produced chemically or Saccharomyces cerevisiae yeasts used in biotechnological synthesis.
The Mechanisms of Action for Resveratrol IV
Revestrol therapy works by defending our cells’ DNA. It’s regarded as one of the strongest antioxidants. Antioxidants function by aiding in the reduction of cell damage brought on by free radicals.
Free radicals are unstable atoms that are created when we are exposed to sunlight, pollution, and the body’s natural fat burning process. They can cause cancer, ageing, and brain degeneration.
The potential of resveratrol to operate as a direct antioxidant and an indirect cellular antioxidant system inducer through modulation of numerous cellular antioxidant pathways, thereby regulating cellular redox status, may contribute, at least in part, to its ability to defend cells.
By preserving the functional capacities of cardiac stem/progenitor cell compartments and mature cardiac cells, improving the cardiac environment by reducing inflammatory state, and reducing unfavorable ventricular remodeling of the diabetic heart, resveratrol protective effect has been shown to improve cardiovascular function in diabetic rats. This results in a notable recovery of ventricular function. By enhancing left ventricle function, reducing cardiac hypertrophy, contractile dysfunction and remodeling, interstitial fibrosis, and plasma BNP levels, resveratrol demonstrated favorable effects in heart failure. Resveratrol works through a number of molecular mechanisms, some of which include the inhibition of prohypertrophic signaling molecules, enhancement of myocardial Ca2+ handling, phosphorylation of prosurvival (Akt-1, GSK-3), stress signaling (MKP-1), and stress signaling pathways, as well as the reduction of oxidative stress and inflammation (iNOS, COX-2 activity, and ROS formation). According to Yan et al., in rats with diabetes-related myocardial infarction, resveratrol prevents the production of endothelial nitric oxide synthase, vascular endothelial growth factor, and suppresses phosphorylation of p38.
How is Resveratrol IV used to Treat Medical Conditions?
- Resveratrol may have an impact on the gut microbiota and the metabolic byproducts of these organisms, such as short-chain fatty acids and intraluminal lipids, and so lessen the symptoms of metabolic syndrome.
- It has been anticipated that resveratrol (3,4′,5-trihydroxy-trans-stilbene) will reduce the severity of cancer and advance cancer treatment.
- Prior to the onset of status epilepticus or after a focal injury, resveratrol treatment can reduce oxidative stress and neuronal death.
- Resveratrol plays a number of neuroprotective roles in a variety of neurodegenerative disorders, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis. It also plays a role in alcohol-induced neurodegenerative disorders.
- Additionally, resveratrol can lessen biochemical and histological harm and exert protective effects against ischemia-reperfusion injury-induced ovarian harm.
- Resveratrol has become and will continue to be a hot topic in many areas, including illnesses of the respiratory system. Indeed, studies have shown that resveratrol helps to improve pulmonary function in the general population and protects against disorders of the respiratory system.
Intravenous IV Resveratrol vs Oral Supplementation
In humans, 75% of resveratrol is absorbed after oral dosing, probably through transepithelial diffusion. However, due to quick and thorough digestion in the intestine and liver, oral bioavailability is poor (1%). Even after repeated or higher dosage delivery, these levels are kept.
Resveratrol glucuronides and sulphates have been found to be the main metabolites found in the plasma and urine by metabolic investigations. Reduced dihydro-resveratrol conjugates and other unidentified highly polar resveratrol metabolites have been reported in the literature.
Although the liver and intestines are the primary sites of metabolism, colonic bacterial metabolism may also be a significant metabolic pathway.
Resveratrol may be more effective at the target site if deconjugating enzymes like -glucuronidase and sulphatase are present, as well as if the substance accumulates in particular tissues. Resveratrol is highly metabolized after oral delivery, resulting in low serum levels of free resveratrol.
According to reports, a mixture of polyphenols (such those found in wine) increases bioavailability. Although some researches have examined the impact of different foods and resveratrol supplementation while under fed or fasted conditions, no conclusive findings have been found.
Consuming resveratrol results in its admission into the hepatic portal system, where it is then processed; avoiding entry to this system may result in higher amounts of free resveratrol.
Free resveratrol levels have increased with intravenous injection and oral transmucosal delivery, however these procedures have also been linked to rapid clearance because of the dispersion of the compound into tissues and phase II metabolism to its sulphate conjugates.
Molecular Structure of Resveratrol IV
The molecular formula of IV Resveratrol is C14H12O3 and its molecular weight is 228.24. The IUPAC name for IV Resveratrol is 5-[(E)-2-(4-hydroxyphenyl) ethenyl] benzene-1,3-diol. Resveratrol is a stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4′ by hydroxy groups.
It has a role as a phytoalexin, an antioxidant, a glioma-associated oncogene inhibitor and a geroprotector. It is a stilbenol, a polyphenol and a member of resorcinols.