This page covers Selenium IV Therapy including its many benefits. IV League provides mobile Selenium IV Therapy.
Powerful mineral selenium is necessary for your body to function properly. It is essential for thyroid and metabolism function and aids in preventing oxidative stress from harming your body.
Your immune system may be strengthened, age-related mental decline may be slowed, and even your risk of heart disease may be decreased with selenium.
Oysters, mushrooms, and Brazil nuts are just a few examples of the many foods that contain this vitamin. Increasing the number of foods in your diet that are high in selenium is a great approach to stay healthy.
Most sulphide ores, including those of copper, nickel, and lead, yield selenium from selenide. Selenium is produced as a byproduct of electrolytic metal refining, specifically from the copper anode mud.
Another source was the no longer usable muck from the lead chambers of sulfuric acid facilities.
There are several ways to purify selenium from these muds. However, the majority of elemental selenium is a byproduct of copper refractory or sulfuric acid production.
Since its inception, the amount of copper produced using solvent extraction and electrowinning (SX/EW) has grown significantly.
The fact that only a negligibly small portion of the selenium in the ore is leached with the copper, this alters the availability of selenium.
Typically, selenium dioxide is extracted from copper purification leftovers for use in the industrial synthesis of selenium.
After that, common manufacturing from the residue starts by producing selenium dioxide through oxidation with sodium carbonate, to create selenous acid, selenium dioxide is combined with water and acidified (oxidation step).
To produce elemental selenium, sulphur dioxide, and sulfuric acid are bubbled together.
Benefits of Selenium IV Therapy
Researchers discovered that adding selenium fertilizer to lettuce crops reduced lead and cadmium buildup. Given a foliar selenium spray, peaches and pears had increased selenium levels and stayed solid and ripe for longer in storage.
- Selenium has demonstrated a positive impact on plant resilience to a variety of environmental stress variables, such as drought, UV-B, soil salinity, and cold or hot temperatures, in modest dosages.
- The inclusion of selenium dioxide lowers the power required to run the electrolysis cells during the electrowinning of manganese. For this purpose, China is the country that consumes the most selenium dioxide. On average, 2 kg of selenium oxide are utilized for every ton of manganese. The manufacturing of glass represents the largest commercial usage of se, contributing for nearly 50% of consumption.
- Se compounds give glass a crimson tint. The green or yellow tints caused by iron impurities that are common in most glass is neutralized by this color. Different selenite and selenate salts are introduced for this purpose. When CdSe and CdS are combined, a red color may be sought for additional applications. Bismuth and selenium are combined to substitute more hazardous lead in brasses. A reduction in lead content in brass was required due to the regulation of lead in drinking water applications, such as the Safe Drinking Water Act of 1974 in the US. EnviroBrass is the name given to the new brass in marketing. Selenium enhances the machinability of steel at values around 0.15%, similar to lead and sulphur. The similar improvement in machinability in copper alloys is brought about by selenium.
- One of the most promising energy storage technologies in the lithium battery family is the lithium-selenium (Li-Se) battery. An advantage of the Li-Se battery over the lithium-sulfur battery is its excellent electrical conductivity. The original solar cells were made of selenium, and the first rooftop solar installation dates back to 1884. Such cells were eventually utilized in photographic light meters without batteries. A component of solar cells is copper indium gallium selenide. Thin films of amorphous selenium (-Se) have been used as photoconductors in flat panel x-ray detectors. Amorphous selenium is used in these detectors to directly transform incident x-ray photons into electric charge.
- In 1933, the first selenium rectifier was used. They were still in use in the 1990s. The catalysts used for the vulcanization of rubber have been modified using small amounts of Organo selenium compounds. Still important in photocopying, photocells, light meters, and solar cells are its photovoltaic and photoconductive qualities. its application in plain-paper as a photoconductor. Numerous photographic manufacturers sell selenium as a toner since it is used to tone photographic prints. The tonal range of black-and-white photographs is enhanced and expanded by selenium, and the longevity of prints is enhanced. In industrial radiography, Se is a gamma source.
History of Selenium IV
In 1817, Jöns Jacob Berzelius and Johann Gottlieb Gahn made the discovery of selenium. Willoughby Smith discovered in 1873 that the amount of ambient light affected the electrical resistance of grey selenium. Its application as a light-sensing cell resulted from this.
Werner Siemens created the first selenium-based commercial items in the middle of the nineteenth century. Alexander Graham Bell created the photophone in 1879 using a selenium cell.
Electric current flow through selenium is related to the amount of light hitting its surface. Light meters and other gadgets of a similar nature were created using this phenomenon. Electronics has used selenium and semiconductor qualities in a wide variety of other ways.
Early in the 1930s, selenium rectifiers were developed, and they eventually superseded copper oxide rectifiers.
These continued in industrial settings until the 1970s, when silicon rectifiers, which were less expensive and much more effective, took their place.
Due to its toxicity to industrial workers, selenium was only subsequently brought to medical attention. Selenium has also come to be known as a significant veterinary poison that manifests in animals who consume high-selenium vegetation.
Biochemist Jane Pinsent found the first indications of specialized biological uses for selenium in microbes in 1954. In 1957, it was found to be necessary for mammalian life. It was demonstrated to be present in two distinct sets of enzymes in the 1970s.
The identification of selenocysteine in proteins came next. Selenocysteine was discovered to be encoded by the codon UGA in the 1980s. Bacteria were used to develop the recoding technique before being used to mammals.
Native, or elemental, selenium is a rare mineral that rarely occurs in nature. The presence of other substances and substances and elements frequently makes it difficult to isolate selenium. Several inorganic forms of selenium, such as selenide, selenate, and selenite, are found naturally, however these minerals are uncommon.
The ubiquitous mineral selenite was given the name “selenium” after the moon long before selenium was discovered, although it is not a selenium mineral and does not contain the selenite ion. Rather, it is a kind of gypsum (calcium sulphate hydrate).
Selenium is typically found in sulphide ores of several metals as an impurity, replacing a small portion of the sulphur. The amino acids selenomethionine, selenocysteine, and methyl selenocysteine include selenium in biological systems. Selenium functions similarly to sulphur in these molecules.
Dimethyl selenide is a different organic selenium molecule that occurs naturally. Some soils have high levels of selenium, and some plants can bioconcentrate selenium.
The most common form of selenium found in soils is selenate, which is similar to sulphate and is easily leached into rivers by runoff. Significant quantities of selenium are present in ocean water. Selenium is typically present in the environment at background levels of no more than 1 ng/m3 in the atmosphere, 1 mg/kg in soil and vegetation, and 0.5 g/L in freshwater and ocean.
Burning coal and mining and smelting sulphide ores are two anthropogenic sources of selenium.
The Mechanisms of Action for Selenium IV
Selenium, however harmful in high concentrations, is a crucial mineral for animals. Some plants may accumulate selenium as a defense against being eaten by animals, but other plants, like locoweed, require selenium and their growth signals the presence of selenium in the soil.
Selenium occurs in plants as a bystander mineral, occasionally in dangerous levels in fodder.
The uncommon amino acids selenocysteine and selenomethionine contain selenium as a component. Selenium, a trace element nutrient, is used by humans to reduce antioxidant enzymes like glutathione peroxidases and some forms of thioredoxin reductase found in animals and some plants (thioredoxin reductase is an enzyme present in all living things, though not all forms of it in plants require selenium).
The three of the four known types of thyroid hormone deiodinases, which activate and then deactivate various thyroid hormones and their metabolites, are used by the thyroid gland and by every cell that uses thyroid hormone.
The iodothyronine deiodinases are the subfamily of deiodinase enzymes that use selenium as the otherwise rare amino acid selenocysteine. The disorder where the body’s own thyroid cells are attacked as foreign may be prevented by selenium.
With a dietary intake of 0.2 mg of selenium, it has been found that TPO antibodies have decreased by 21%. Increased dietary selenium decreases the harmful effects of mercury, although it only works at low to modest mercury concentrations.
The permanent inhibition of selenoenzymes, which are necessary to prevent and cure oxidative damage in brain and endocrine tissues, appears to be one of the molecular causes of mercury toxicity.
Scientists are investigating the potential effects of the antioxidant selenoneine, which is generated from selenium and has been reported to be present in the blood of bluefin tuna, on inflammatory and chronic illnesses, methylmercury detoxification, and oxidative damage.
It appears that selenium levels increase together with mercury levels in marine fish. Researchers are unaware of any examples of ocean fish having mercury levels higher than selenium levels.
Prokaryotic selenoprotein families have driven the evolution of selenocysteine, an amino acid, since roughly three billion years ago. In bacteria, archaea, and eukaryotes, selenium is integrated into numerous prokaryotic selenoprotein families as selenocysteine, where selenoprotein peroxiredoxins guard bacterial and eukaryotic cells against oxidative damage.
GSH-Px seleniprotein families and eukaryotic cells’ deiodinases appear to have descended from bacteria, according to phylogenetic analysis. Diverse species including green algae, diatoms, sea urchins, fish, and chickens all possess the selenocysteine-containing variant of the disease.
The tiny reducing molecules glutathione and thioredoxin are processed by selenium enzymes. Using glutathione, one class of selenium-containing molecules known as glutathione peroxidases degrades peroxide and restores per oxidized cell membranes.
Thioredoxin reductase, a selenium-containing enzyme found in various plants and animals, produces reduced thioredoxin, a dithiol that provides an electron supply for peroxidases as well as the critical reducing enzyme ribonucleotide reductase, which converts RNA precursors into DNA precursors.
Another family of eukaryotic selenoproteins with a known enzymatic function is the deiodinase isoenzymes. Iodides and iodides from iodothyronines can both be extracted by deiodinases.
Thus, they play a role in the regulation of thyroid hormones by helping to prevent thyrocyte damage from H2O2 generated during the manufacture of thyroid hormones. New selenoproteins evolved as mammalian GSH-Px enzymes about 200 million years ago.
How is Selenium IV Therapy Used to Treat Medical Conditions
1. Selenium is a potent antioxidant that fights oxidative stress and aids in protecting your body from chronic diseases like cancer and heart disease. Antioxidants are substances found in meals that stop cell deterioration brought on by free radicals.
Free radicals are naturally produced by-products of bodily functions including metabolism on a daily basis. Free radicals frequently receive a bad rap, although they are vital to your health. They carry out crucial tasks, like as keeping your body healthy.
However, factors like stress, alcohol consumption, and smoking might result in a surplus of free radicals. Oxidative stress results from this, harming healthy cells. Chronic diseases like heart disease, Alzheimer’s, and cancer, as well as early aging and the risk of stroke, have all been related to oxidative stress. antioxidants, such as selenium assist minimize oxidative stress.
They function by scavenging surplus free radicals and shielding cells from oxidative stress-related harm.
2. Selenium supplementation may help patients undergoing radiation therapy live better lives, while higher blood levels of selenium may guard against some malignancies.
Selenium helps lessen oxidative stress in addition to reducing the incidence of some malignancies.
Selenium’s capacity to lessen DNA damage and oxidative stress, strengthen your immune system, and eliminate cancer cells has been credited with this.
Having a high blood level of selenium was linked to a lower risk of several cancers, including breast, lung, colon, and prostate cancers, according to a study of 69 studies involving over 350,000 participants.
It’s important to remember that this impact was only linked to selenium that was consumed naturally through food rather than supplements. However, some data indicates that selenium supplementation may lessen negative effects in patients receiving radiation therapy.
For instance, one study revealed that giving women with uterine and cervical cancer oral selenium supplementation enhanced their general quality of life and decreased radiation-induced diarrhea.
3. Selenium may lower your risk of developing heart disease and keep oxidative stress under control, which is good for your heart. Due to the association between low selenium levels and an increased risk of heart disease, a diet high in selenium may help maintain heart health.
A 50% increase in blood selenium levels was linked to a 24% lower risk of heart disease in an analysis of 25 observational studies. One of the major risk factors for heart disease, inflammation indicators in your body, may be reduced by selenium.
For instance, an analysis of 16 research with strict controls, involving more than 433,000 heart disease patients, revealed that taking selenium supplements reduced levels of the inflammatory marker C-reactive protein (CRP). Additionally, it raised levels of the potent antioxidant glutathione peroxidase.
This suggests that selenium may help lessen the risk of heart disease by reducing oxidative stress and inflammation in your body. The development of plaque in arteries, also known as atherosclerosis, has been associated with oxidative stress and inflammation. Strokes, heart attacks, and heart disease are just a few of the hazardous health issues that atherosclerosis can cause. Including foods high in selenium in your diet is a fantastic approach to minimize oxidative stress and inflammation.
4. People with Alzheimer’s disease may benefit from a diet high in selenium since it may help prevent mental decline and improve memory loss. Alzheimer’s disease is a terrible sickness that impairs thinking and conduct while also causing memory loss.
In the US, it is the sixth most common cause of death. Alzheimer’s patients are becoming more numerous. Therefore, it is crucial to develop ways to stop this degenerative illness. It is thought that oxidative stress plays a role in the development and progression of neurological conditions like Parkinson’s, multiple sclerosis, and Alzheimer’s.
Numerous investigations have revealed that selenium levels in the blood are lower in people with Alzheimer’s disease. Additionally, some studies have shown that antioxidants, which may be found in both food and dietary supplements, may help Alzheimer’s patients remember things better.
In a tiny study, it was discovered that giving patients with mild cognitive impairment one Brazil nut per day as a supplement enhanced verbal fluency and other mental abilities. Furthermore, a lower incidence of Alzheimer’s disease has been linked to the Mediterranean diet, which is heavy in foods high in selenium, such as seafood and almonds.
5. The generation of thyroid hormones depends on selenium, which also shields the thyroid gland from oxidative damage. More research is required, although selenium may benefit those with Hashimoto’s disease and other thyroid conditions.
For your thyroid gland to operate properly, selenium is crucial. In actuality, thyroid tissue has the highest concentration of selenium of any human organ. This potent mineral plays a crucial part in the creation of thyroid hormones and aids in defending the thyroid from oxidative damage.
You need a healthy thyroid gland because it controls growth and development and regulates your metabolism. Selenium deficiency has been linked to thyroid disorders like Hashimoto’s thyroiditis, a form of hypothyroidism when the thyroid gland is attacked by the immune system.
Low serum levels of selenium were linked to a higher risk of hypothyroidism and autoimmune thyroiditis, according to an observational study including more than 6,000 patients. Supplements containing selenium may also be helpful for persons with Hashimoto’s disease, according to certain research.
According to one study, consuming selenium pills every day for three months reduced thyroid antibodies. It also helped patients with Hashimoto’s illness feel better emotionally and generally. Before selenium supplements are suggested for those with Hashimoto’s disease, more research is necessary.
6. Your immune system needs selenium to be healthy and function properly. People who have HIV, influenza, TB, and hepatitis C may benefit from higher amounts of selenium by having stronger immune systems.
Your immune system recognizes and fends off possible dangers to keep your body healthy. These consist of parasites, viruses, and bacteria. In maintaining the health of your immune system, selenium is crucial. This antioxidant assists your body in reducing oxidative stress, which lowers inflammation and improves immunity.
Increased selenium levels in the blood have been linked to improved immunological function, according to studies. Deficit, on the other hand, has been demonstrated to impair immune cell activity and may cause a sluggish immunological response.
Supplements have been proven to reduce hospitalizations and improve symptoms for patients with HIV, whereas studies have linked deficiencies to a higher risk of death and disease progression in those with the virus. Supplemental selenium may also support immune system vigor in those with hepatitis C, TB, and the flu.
7. Due to its capacity to reduce cellular inflammation, selenium may be advantageous for those who suffer from asthma. However, more study is required. The airways that carry air into and out of the lungs are impacted by asthma, a chronic illness.
Wheezing, shortness of breath, chest tightness, and coughing are some of the symptoms that result from these airways becoming irritated and starting to narrow. Increased levels of oxidative stress and inflammation in the body have been linked to asthma.
According to some research, selenium may help lessen the symptoms of asthma because of its capacity to reduce inflammation. According to research, selenium levels in the blood are lower in patients with asthma. In fact, research found that patients with asthma who had greater blood selenium levels had better lung function than those who had lower levels.
Supplemental selenium may also lessen asthmatic symptoms. For instance, one study discovered that providing 200 mcg of selenium daily to asthma sufferers decreased their need for corticosteroid drugs to manage their symptoms.
To properly comprehend selenium’s function in the onset and management of asthma, however, more extensive investigations are required due to the contradictory nature of the available evidence.
Intravenous vs Oral Supplementation
Clinical insufficiency of selenium (Se), an essential vitamin for humans, can have catastrophic implications. Therefore, all patients who require parenteral nourishment (PN) should have it intravenously. Moreover, this supplement should be given from the start of the PN course because the effects of inadequate status are erratic and uncertain. Most patients getting PN at home or following surgery will be able to get by on 60 to 100 mcg per day. Patients who start PN with low selenium levels could need more.
Patients who are critically unwell or who have suffered serious burns can need further care. For burn victims, there is strong evidence that selenium supplementation up to 400 mcg/day is useful, however there is conflicting data on the effectiveness of high-dose selenium in the treatment of severe sepsis. Selenium levels should be monitored by measuring plasma selenium along with a measure of systemic inflammatory response syndrome, such as C-reactive protein, when higher Se supply is employed or in long-term PN.
Numerous research questions exist, such as which biochemical measurements are most accurate indicators of tissue function, particularly immune function in critically ill patients, the clinical repercussions of suboptimal biochemical Se status, whether high-dose Se improves outcomes in critically ill patients, and whether extra Se should always be given along with extra intakes of other antioxidants.
Over a period of time, it is infused into a vein. The mineral selenium is found in soil and naturally appears in a number of foods, including whole grains, Brazil nuts, sunflower seeds, and seafood. Although the body cannot generate selenium, it is essential for healthy thyroid and immune system operation.
To treat or prevent selenium insufficiency, selenium is utilized. The autoimmune thyroid condition Hashimoto and thyroiditis, as well as excessive cholesterol, have both been treated with selenium in alternative medicine. The FDA has not given its approval to all applications for selenium. Selenium shouldn’t be substituted for any medications that your doctor has prescribed for you.
Selenium can also be used for other things not covered in this user manual. Consult your doctor before considering the usage of herbal supplements. You might also think about speaking with a doctor who specializes in the use of herbal remedies and dietary supplements.
Use selenium as recommended on the container or by your doctor, pharmacist, or other healthcare provider if you decide to do so. Selenium use over a long period of time at quantities greater than 400 mcg per day can result in fatalities or major medical issues.
Use only as much of this product as the label instructs. With ageing, a higher daily intake of selenium is advised. Pay attention to your doctor’s directions.
Molecular Structure of Selenium IV
The molecular formula of selenium is O2Se or SeO2 and its molecular weight is 110.96. IUPAC name of selenium is Selenium Oxide.