This page covers Vitamin B Complex IV Therapy. IV League provides mobile Vitamin B Complex IV Therapy.
All of the key water-soluble vitamins in the vitamin B family, including vitamins B1, B2, B3, B5, and B6, are included in the B Complex Shot. B vitamins are crucial for maintaining a healthy body.
It directly affects how much energy we have, how well our brains work, and how our cells perform. Some are anti-oxidants that reduce the damage that free radicals do to cells and the development of disease.
Others increase blood cell production or immune system activity. B vitamin fusion keeps you going strong throughout the day. You ensure that your body is in the best possible health by adding an IV drip to them.
When administered intravenously, vitamin B is absorbed by the body more effectively than when taken orally.
Some illnesses, such as celiac disease, Crohn’s disease, or other autoimmune disorders, can make it even more difficult for your body to benefit fully from oral vitamin B.
Vitamin B complex is an amalgamation of eight B vitamins, all of which work differently in our body:
- Thiamine = Vitamin B1
- Riboflavin = Vitamin B2
- Niacin = Vitamin B3
- Pantothenic acid = Vitamin B5
- Pyridoxine = Vitamin B6
- Biotin= Vitamin B7
- Folic acid = Vitamin B9
- Cobalamin = Vitamin B12
To receive adequate vitamin B, a healthy diet is typically sufficient. However, there are situations when your body does not absorb enough vitamins, which might result in medical issues.
People who do not get enough vitamin B may get skin rashes, exhaustion, anemia, or irritation. Depression and nausea are additional signs of low vitamin B levels.
Benefits of Vitamin B-Complex IV Therapy
B vitamins promote a variety of bodily processes, such as healthy neuron function, red blood cell formation, regular digestion, and hormone production. Vitamin B complex helps with metabolism, maintains healthy physiological and nervous system functioning, and lessens exhaustion and tiredness when paired with other nutrients like magnesium and vitamin C. Benefits of Vitamin B can be summarized as:
- Increases energy levels;
- Promotes deeper sleep;
- Fights fatigue and tiredness;
- Helps maintain mental clarity;
- Contributes to healthy skin, hair, nails and complexion; and
- Helps to keep food cravings under control
Following are the individual benefits of each of the elements included in Vitamin B complex:
- Thiamine – Thiamine is essential for cell growth and function, supports muscle contraction, and speeds up the body’s metabolism of protein and lipids.
- Riboflavin – The coenzymes involved in the breakdown of drugs and lipids are supported in their activity by riboflavin. It promotes bodily growth, the generation of hormones and energy. Additionally, vitamin B2 supports the health of the skin, muscles, nerves, eyes, and liver and is crucial for embryonic development.
- Niacin – Niacin, also known as niacinamide, is necessary for the production of enzymes and the conversion of food into energy. It promotes healthy digestion and nervous system function, stimulates DNA repair, and decreases blood cholesterol.
- Pantothenic Acid – The creation of hormones and cholesterol is aided by pantothenic acid, a crucial nutrient that supports the neurological system and brain function. In addition, vitamin B5 stimulates the metabolism of poisons and medications, promotes wound healing, and is necessary for regular metabolism. Numerous symptoms, such as nausea, irritability, sadness, sleeplessness, and exhaustion, can be caused by deficiency.
- Pyridoxine – Another necessary B vitamin, pyridoxine, is involved in the metabolism of critical amino acids and the synthesis of neurotransmitters. It aids in the body’s ability to make red blood cells, which carry oxygen from the lungs to all of the organs. Additionally, vitamin B6 promotes normal cell division, the metabolism of carbohydrates, fats, and proteins, as well as a strong immune system. It boosts brain and eye health, lessens the risk of heart disease, and lessens the symptoms of depression.
- Biotin – A B complex vitamin, biotin is also important for maintaining healthy skin, hair, and nails in addition to supporting fat and carbohydrate metabolism. It participates in a variety of cellular processes, including the production of energy for the entire body. Additionally, biotin promotes healthy nervous system function, improves liver and brain function, and controls blood glucose levels.
- Folate – Folate, also known as folic acid when taken as a supplement, is essential for the growth and division of cells as well as for the production of white and red blood cells and the digestion of amino acids. It promotes the neurological system and brain functioning, helps with DNA synthesis and repair, and hastens wound and injury healing. Early pregnancy and times of fast growth, such as puberty and youth, require a lot of vitamin B9. According to research, it may aid in the treatment of dementia, heart disease, and depression.
- Cobalamin – And finally, cobalamin is necessary for bone health, blood cell production, and DNA synthesis. It lessens the risk of osteoporosis and eye conditions, aids in the prevention of anemia and birth abnormalities, and alleviates the signs and symptoms of sadness.
History of Vitamin B-Complex IV Therapy
“Vitamin B” was once thought to be a single nutrient. Researchers later discovered these extracts contained several vitamins, which were given distinguishing numbers, leading many people to the erroneous conclusion that these vitamins have a special relationship to each other.
Further adding to confusion has been the “unofficial” designation of other, non-essential vitamins, as members of the B-complex, such as choline, inositol, and para-aminobenzoic acid (PABA).
The history of the vitamin B complex’s discovery begins in 1889, when a Dutch doctor by the name of Christiaan Eijkman was researching beriberi, an endemic disease that occasionally resulted in weakness, weight loss, confusion, and even death, while working in the Dutch East Indies (modern-day Indonesia).
In regions where refined rice dominated the diet, including in southern and southeastern Asia, the disease was widespread. A Polish biochemist working in London named Casimir Funk hypothesized that hitherto unidentified chemical compounds, which he called “vitamines,” were necessary in minute amounts to preserve health in 1911.
This word was created by combining the words “vital” and “amine,” which refers to an organic molecule’s nitrogenous group. Although the word had already gained popularity and the final “e,” researchers later discovered that not all vitamins have amine structures.
Elmer McCollum, a scientist at the University of Wisconsin, identified two distinct vitamin species in 1913 and named them “fat-soluble factor A” and “water-soluble factor B.”
Below is the detailed discovery of all vitamins of B complex in a chronological order:
- The anti-beriberi factor crystals were isolated in 1926 by Dutch chemists Barend Jansen and Willem Donath from extracts of rice polishing. The first vitamin to be discovered was the anti-beriberi factor, which supported Hopkins and Funk’s theories. Later, it was known as thiamine or vitamin B1 (also spelled thiamin).
- In 1922, Richard Kuhn in Germany and Theodor Wagner-Jauregg in Austria discovered vitamin B2 (riboflavin). In Germany in 1933, Kuhn and Paul György isolated the chemical. Additionally, Kuhn created a synthetic approach to riboflavin.
- György and colleagues originally identified vitamin B6 (pyridoxine) in 1934, and Samuel Lepovsky of the University of California, Berkeley first isolated the active ingredient in 1938. In 1939, Folkers and his Merck coworker Stanton Harris, working in tandem with Kuhn in Germany, identified the structure of pyridoxine. Following this, Merck announced the production of vitamin B5 (pantothenic acid) in 1940.
- In 1947, Folkers and his team isolated vitamin B12 (cobalamin), producing tiny, bright red crystals of the vitamin. The following year, this new compound was tested on a patient who suffered from pernicious anemia, curing her. Cobalamin was later found to be a key growth factor in animals. This realization led to the practice of enhancing animal diets with the vitamin, which led to greatly increased yields for livestock farmers.
- Before vitamins were discovered and widely available, diseases brought on by malnutrition caused an immeasurable human toll. For pharmaceutical firms like Merck, the study and creation of these necessary nutrients marked a turning point. By eradicating the plague of malnutrition, their work significantly benefited both human and animal health.
Dr. John Myers created and gave the first IV vitamin drips in the 1970s. His investigation produced the well-known Myers’ Cocktail. These infusions typically last 20 minutes to an hour, take place in a medical office, and are under the supervision of a qualified medical expert.
Your body is obtaining a higher concentration of the vitamins itself while you are receiving an IV vitamin drip.
The amount of a vitamin that can be absorbed when given orally is constrained since it is broken down in the stomach and digestive tract (50 percent). But if the vitamin is administered intravenously, it is absorbed at a significantly faster rate (90 percent).
The Mechanisms Of Action for Vitamin B-Complex IV
In a significant fraction of the enzymatic pathways that underlie every aspect of cellular physiological functioning, B vitamins work as coenzymes.
The biologically active form of the vitamin forms a coenzyme with a protein “apoenzyme” to form a “holoenzyme,” extending the potential range of processes that the resulting enzyme can catalyze.
Methionine synthase and L-methylmalonyl-CoA mutase enzymes require vitamin B12 as a cofactor. For the synthesis of the purines and pyrimidines that make up DNA, methionine synthase is necessary. L-methylmalonyl-CoA mutase is a crucial enzyme needed for the breakdown of propionate, which is a step in both fat and protein metabolism.
It transforms L-methylmalonyl-CoA to succinyl-CoA. The neurological symptoms of vitamin B12 deficiency are thought to be caused by a shortage of vitamin B12 cofactor in the aforementioned reaction and the buildup of methylmalonyl CoA that follows. Hemoglobin is also produced through the production of succinyl-CoA.
Vitamin B12 is necessary for the production of methionine from homocysteine in tissues. Methionine is necessary for the synthesis of S-adenosylmethionine, a methyl donor for more than 100 substrates, including proteins, lipids, hormones, DNA, and RNA.
Tetrahydrofolate cannot be converted back into 5-methyltetrahydrofolate without vitamin B12, which can result in functional folate deficiency.
This process, in which the methyl group of methyltetrahydrofolate is transferred to homocysteine to create methionine and tetrahydrofolate, requires folate as a co-factor as well as methylcobalamin (vitamin B12).
Folic acid is retained in developing red blood cells thanks to vitamin B12’s incorporation of the substance. Megaloblastic anemia develops as a result of a vitamin B12 deficiency and the disruption of this response.
Vitamin B Complex IV Therapy Treatment for Medical Conditions
How Is Vitamin B-Complex IV Therapy Used To Treat Canker Sores?
Oral ulcers, sometimes referred to as canker sores, may be helped by vitamin B12. When taken in conjunction with main treatment, a B12 ointment reduced pain more effectively than a placebo, according to a double-blind research.
How Is IV Vitamin B-Complex Used To Treat Anxiety And Depression?
According to the authors of a 2018 study, there is a link between vitamin B12 levels and the onset and manifestation of anxiety and depression. They state that participants who were depressed or anxious had lower levels of B12 than those who were in the control group.
This might allude to a connection between the two. But more investigation is required.
B vitamins may occasionally be able to alleviate depression, according to a 2015 meta-analysis. According to the study, taking some B vitamins on a regular basis for a few weeks to years can lower the risk of relapsing into depression.
A small-scale 2019 study conducted in India raised the possibility that B9 and B12 deficiency may contribute to sadness and anxiety, however the elevated risk was not statistically significant.
How Is IV Vitamin B-Complex Used To Treat Migraine?
According to several studies, the following B vitamins may help reduce migraines with aura:
- B vitamins (B6, B9, and B12)
Additionally, according to the researchers, vitamin B2 may prevent migraines by regulating biological processes that affect mitochondrial malfunction. The authors of a review study published in 2017Trusted Source examined how vitamin B2 affects migraine. They claim that this vitamin is well-tolerated and efficient at lowering the frequency of migraine attacks in adults, although they advise more study.
Intravenous IV Vitamin B-Complex vs. Oral Supplementation
IV treatment is unquestionably superior to conventional oral supplementation in terms of hydrating your body and supplying specialized nourishment. Your body absorbs a great deal more of the nutrition since it is provided more quickly.
Intravenous: Cobalamin and vitamin B12 injections, part of the vitamin B complex, are rapid, painless, and efficient treatments for pernicious anemia that can also be administered to other parts of the body. The bioavailability of intramuscular injections delivered with a needle might range from 75% to 100% greater. Due to increased absorption, those who receive vitamin B12 injections, for instance, benefit from the treatment more quickly.
Oral: Out of the two techniques, oral supplements offer a simpler, quicker strategy to revive. Daily vitamin B pills are accessible at the majority of pharmacies and vitamin stores, are reasonably priced, and can be included into practically any morning routine.
However, the liver and digestive system help us lose a large portion of the benefits of vitamins when we consume them orally, which reduces the bioavailability of the supplement.
Molecular Structure of Vitamin B-Complex IV
The core of the vitamin consists of a corrin ring with a central cobalt atom. Corrin contains four pyrrole rings linked together and vaguely resembling structurally the porphyrin ring in heme. An inactive form of the vitamin contains a displaceable CN group bound to the cobalt; hence the early name cyanocobalamin for one of its more familiar forms. The cobalt atom in the ring can have a +1, +2, or +3 oxidation state.
The fifth valence (below the ring plane) has a dimethylbenzimidazole attached to the cobalt and the six can be either a methyl group, an –OH group, or a 5′-deoxyadenosyl group depending on the reaction or enzyme. As noted, 5′-deoxyadenosylcobalamin is the most common form of the coenzyme.
The 5′-deoxyadenosylcobalamine arises by an attack on the 5′-carbon of ATP by the Co+, which displaces the entire triphosphate group of ATP, a rare action in biochemistry.
Known enzymes that require B12 fit one of two functional categories: those that transfer methyl groups from the coenzyme to the substrate, and those that take part in positional rearrangement of neighboring groups on the substrate, or group transfer reactions.
Vitamin B Complex is also known as known as cyanocobalamin. Its molecular formula is C63H88CoN14O14P while its molecular weight is 1355.4.
